Multiple Sclerosis (MS) Treatments Reversing Brain Damage Are Closer

An international team of scientists recently reported breakthrough research of myelin regrowth in rodents.  The team lead, Dr. Denise Fitzgerald described the finds as “an important step forward in understanding how the brain and spinal cord in naturally repaired.”

Multiple Sclerosis (MS) is a neurological disease in which the immune system mistakenly attacks the tissue of the central nervous system – consisting of the brain, spinal cord, and nerves.  The immune system attacks and destroys myelin – which is the fatty, protective covering around nerve fibers.  When the myelin is damaged, nerve signals traveling to and from the brain are disrupted.  The disruptions cause impaired mobility, fatigue, vision issues, pain, numbness, altered sensations, and cognitive issues.  MS is more common in women than men and is the most common neurological disease in young adults.  See, http://www.nationalmssociety.org/What-is-MS/MS-FAQ-s#question-What-is-multiple-sclerosis

The scientists discovered that certain immune regulatory cells have a role in encouraging myelin regrowth.  The scientists were able to determine that subjects with deficient regulatory cells had significantly impaired myelin regrowth.  When regulatory cells were provided to the subjects the myelin regrowth was restored.

Dr. Sorrel Bickley, head of biomedical research at the U.K. MS Society, stated “This exciting study gives us an important understanding of how myelin repair can be promoted, which could open up new areas for treatment development. “

For more detailed information, please see: Regulatory T cells promote myelin regeneration in the central nervous system.  

Loyd J. Bourgeois
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